Porphyria teeth discoloration

In porphyria cutanea tarda, exposed skin shows abnormalities similar to those found in variegate porphyria. They range from slight fragility of the skin to persistent scarring and disfiguration. Due to fragility of the skin, minor trauma may induce blister formation. Areas of increased and decreased pigment content may be noted on the skin If you have congenital erythropoietic porphyria (CEP) or hepatoerythropoietic porphyria (HEP), you may have reddish-brown staining on your teeth as a result of porphyrin accumulation. Because of this, you might want veneers, crowns, or facings, all part of cosmetic dentistry, to cover such discoloration

Porphyrin deposition may lead to corneal ulcers and scarring, reddish-brown discoloration of the teeth (erythrodontia), and mild bone loss and/or expansion of the bone marrow. The phenotypic spectrum, however, is broad and ranges from non-immune hydrops fetalis in utero to late-onset disease with only mild cutaneous manifestations in adulthood Porphyria in swine is rare and incompletely described. Affected pigs have discoloration of teeth and excessive uroporphyrin in urine. In contrast to CEP in cattle and people, affected swine are not anemic and do not present with signs of photosensitization • It leads to a discoloration of the teeth, due to a deposition of porphyrin pigments. 107. • The deposition of red-brown porphyrin pigments in the tooth substance causes a characteristic red discoloration of the teeth, which is most marked in the cervical area and is reduced towards the occlusal surface

In the management of patients with stained teeth it is very important to know and understand the mechanisms behind tooth discolorations as well as the clinical features of different types of tooth staining, in order to make a correct diagnosis. The teeth are an integrated part of facial aesthetics and are involved in a complex social, cultural an Tooth discoloration is abnormal tooth color, hue or translucency. External discoloration is accumulation of stains on the tooth surface. Internal discoloration is due to absorption of pigment particles into tooth structure. Sometimes there are several different co-existent factors responsible for discoloration Congenital Erythropoietic Porphyria (CEP) is a very rare disease with approximately 150 patients reported in the world. CEP is often manifested shortly after birth with dark urine and sunlight sensitivity causing blistering and skin fragility. Later, brownish, fluorescent teeth, increased hair growth, and pronounced scarring may occur Erythrodontia, a pinkish-brown discoloration of teeth due to porphyrin deposition in the dentin, is common; these teeth glow with a red fluorescence under ultraviolet light. The pathogenesis of CEP is due to accumulation of the isomer I porphyrins, which are autooxidized to the corresponding porphyrins that catalyze phototoxic reactions

angle the tooth is viewed from affect the apparent tooth colour. Light is composed of differing wavelengths and the same tooth viewed under different conditions will exhibit a different colour, a phenomenon known as metamerism. In judging tooth colour it is best if the light source used is stan-dardised to reduce the effects of metamerism B. Tetracycline discoloration of teeth. C. Epidermolysis bullosa. D. Bullous pemphigoid. E. Porphyria cutanea tarda. Discussion. The answer is E: porphyria cutanea tarda. In this photograph, the. The complaint is a result of mild-to-severe discoloration of any or all portions of the teeth, typically the anterior teeth. Stains associated with foods (eg, blueberries), beverages (eg, tea,.. Affected animals have reddish brown discoloration of the teeth, bones, and urine at birth that continues for life. Abnormal byproducts accumulate in the skin and cause severe sensitivity to the sun (called photosensitivity) 1. J Oral Pathol. 1972;1(4):159-71. The pigmentation of dental tissues in erythropoietic (congenital) porphyria. Trodahl JN, Schwartz S, Gorlin RJ

Congenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea Intrinsic tooth discolorations may arise from developmental tooth abnormalities or an endogenous material that is incorporated into tooth structure during development. Because these do not represent surface stains, removal is not possible reddish-brown discoloration in the teeth, and sclerotic and osteolytic round lesions in the skull and jaws. 10. CEP demonstrates unique dental-craniofacial porphyria, dentists should be in dialogue with the patient's physician. As management of patients with porphyrias, pharmacological concerns have been. Porphyria is a group of liver disorders in which substances called porphyrins build up in the body, negatively affecting the skin or nervous system. The types that affect the nervous system are also known as acute porphyria, as symptoms are rapid in onset and short in duration. Symptoms of an attack include abdominal pain, chest pain, vomiting, confusion, constipation, fever, high blood.

Why Are My Teeth Discolored? Part 2 | Intelligent Dental

color change and hence tooth discoloration [1]. 2. Etiology Tooth discoloration can be divided into two main groups: intrinsic stains and extrinsic stains. Intrinsic stains could be due to metabolic, inherited, iatrogenic, traumatic, idiopathic, or ageing causes. Metabolic disorders such as alkaptonuria and congenital erthropoietic porphyria. Endogenous stains Internal discoloration of teeth may occur as the result of decomposition of blood pigments associated with the death of the pulp. Such pigments give the tooth a grayish or blue-black discoloration, the teeth occsionally may be discolored by blood-borne pigments associated with the severe systemic disease or inborn errors of pigment metabolism such as congenital porphyria The change in color may affect the entire tooth, or it may appear as spots or lines in the tooth enamel. Enamel is the hard outer layer of the tooth. The discoloration can be either temporary or permanent. It may also appear on many teeth or only one area

Congenital erythropoietic porphyria Genetic and Rare

Many things can cause teeth to become discolored. The change in color may affect the entire tooth, or it may appear as spots or lines in the tooth enamel. Enamel is the hard outer layer of the tooth. Porphyria (a group of disorders caused by a buildup of natural chemicals in the body Congenital erythropoietic porphyria is a rare autosomal recessive disorder that usually presents with marked skin photosensitivity, hypertrichosis, blistering, scarring, milia formation and dyspigmentation of the photo-exposed areas. Three adult siblings (two sisters and one brother) are presented here with variable degree of skin manifestations Hepatoerythropoietic Porphyria: This subtype differs from the others in that it involves an overproduction of haem. Skin-related symptoms can manifest in infancy. In severe cases, it can result in distortion of the fingers and face and the teeth usually exhibit discoloration. Bone abnormalities are also common. Clinical Complication

Acute porphyria is said to occur predominantly in women, usually in the third or fourth decades. Photosensitivity is rare. Pigmentation of the teeth does not occur although the skin may show diffuse pigmentation. Dark brown or red discoloration of the urine may appear intermittently, usually coincident with clinical activity of the disease Affected teeth generally are yellowish when they erupt and become darker and browner after exposure to light. The degree of clinical discoloration of the teeth is affected by which particular tetracycline preparation has been taken, the dosage and the age of the patient at the time of administration of the drug

Congenital erythropietic porphyria-oral manifestations and dental treatment in childhood: a case report. Extrinsic tooth discoloration by metals and chlorhexidine. Clinical staining produced. causing intrinsic tooth discoloration. 2. Amelogenesis imperfecta affects both primary and secondary dentitions 3. Dental dysplasia occurs in two types; teeth with type 2 dental dysplasia have amber, blue or brown translucence. 4. Other dental diseases may be as Erithropoietic porphyria and epidermolysis bullosa. Medications 1 Porphyria · It is Bleaching of vital teeth is indicated primarily for patients with generalized yellow, orange, or light brown extrinsic discoloration of teeth (including chlorhexidine staining), even though it may be useful in ameliorating mild cases of tetracycline-induced intrinsic discoloration of teeth and fluorosis

Porphyria - NORD (National Organization for Rare Disorders

Dental injury: Traumatic injury may cause discoloration of the teeth due to bleeding or due to exposure of dental tissue.Injuries may cause the teeth to become dark gray, yellow, or pink based on the injury .; Food: Some foods with natural color may stain the teeth temporarily.Examples of such foods are tomato and soy sauce, candies, berries, chocolate, pickles, and beets Also known as Günther's disease,erythropoietic porphyria is hallmarked by unsightly pigmented scarring, hirsuteness and red-tinged teeth; it has been proposed as the origin of the werewolf legend. 1 The porphyrias highlighted in the following article are of the hepatic kind

Pre-eruptive discoloration may be the result of exposure to high levels of fluoride (fluorosis); Tetracycline administration, inherited developmental disorders (for example, Erythroblastis Foetalis, Porphyria, Thalassemia or Sickle Cell Crises) or trauma to the developing tooth. See the brown and white discoloration of upper right central. Snowcapped teeth. Traumatic opacities. Red-brown. porphyria. Gray. Dentinogenesis imperfect. Tetracycline staining. Mostly these diseases affect the teeth during their growth stage or before the eruption time. Yellow or Brown color teeth are seen in decidious teeth as well in cases like elevated bilurubin in body due to jaundice Porphyria cutanea tarda (PCT) typically is acquired rather than inherited, although the enzyme deficiency may be inherited. Certain triggers that impact enzyme production — such as too much iron in the body, liver disease, estrogen medication, smoking or excessive alcohol use — can cause symptoms There are two different kinds of porphyria that affect cats: acute intermittent porphyria (AIP) and congenital erythropoeitic porphyria (CEP). The most obvious symptoms of porphyria in cats are discolored, reddish brown teeth (erythrodontia), and reddish brown urine. Normally when a cat has reddish brown urine it will be full of red blood cells Congenital erythropoietic porphyria (CEP) is an autosomal recessive cutaneous porphyria caused by mutations in the gene coding for uroporphyrinogen III synthase (UROS).1,2 Phototoxic reactions result from the accumulation of biologically inert type I porphyrins, predominantly in the skin, red blood cells, bones, and teeth

Going to the Dentist When You Have Porphyria - Porphyria New

Bovine congenital porphyria (pink tooth), with a note on five cases observed in Jamaica. Cornell Vet. 1958; 48: 430-439. PubMed; Google Scholar]The clinical signs have included pink or reddish-brown discoloration of the teeth (Fig. 1B) and bones, amber or red urine, and orange/red or red fluorescence of the teeth. The inborn errors of heme biosynthesis, the porphyrias, are metabolic disorders, each resulting from the deficiency of a specific enzyme in the heme biosynthetic pathway (Figure 1; Table 1). 1,2 These enzyme deficiencies are inherited as autosomal dominant, autosomal recessive, or X-linked traits, with the exception of the most common porphyria, porphyria cutanea tarda (PCT), which usually is. The symptoms of acute porphyria can develop quickly and last for days or weeks. You might have an imbalance of salt in your body along with this type of porphyria. You may notice changes in your.

Congenital erythropoietic porphyria (CEP) is a rare hereditary autosomal recessive disease which has never been reported in Zebu cattle. A 3-day-old Gir calf showed teeth discoloration, fever, dehydration, and dyspnea. The main gross findings were pink-colored teeth, red-brown periosteum and bone marrow, and a fluorescent bright pink coloration. Consultations with the appropriate medical providers may be required if the underlying etiology of tooth discoloration is related to a systemic disease (eg, porphyria, AI). Endodontists, prosthodontists, periodontists, and oral and maxillofacial surgeons and/or dental specialists may assist with therapies patients with stained teeth, it is important to know and understand the mechanisms behind the tooth discoloration, and the clinical features of different types of tooth staining to ensure a correct diagnosis. The reasons for discolorations can be of medical, genetic, or odontological origin.[20,21] A number o

Congenital Erythropoietic Porphyria - American Porphyria

Congenital erythropoietic porphyria. (A) A severely affected CEP patient who has had multiple sun-induced skin lesions. The cutaneous bullae and vesicles burst and became secondarily infected, leading to bone involvement and resultant loss of facial features and digits. (B) Note his brownish discolored teeth, which fluoresce (erythrodontia. In congenital porphyria, both the deciduous and permanent teeth may have red or brownish discoloration but always fluoresce red from the pigment deposited in the dentin. Congenital hyperbilirubinemia causes a yellowish tooth discoloration. Teeth can be whitened (see table Tooth-Whitening Procedures) Reddish, brown opalescent discoloration of teeth in normal light. Congenital erythropoietic porphyria (CEP) is characterized in most individuals by severe cutaneous photosensitivity with blistering and increased friability of the skin over light-exposed areas reported on the rarity of a permanent pink or red discoloration of isolated teeth during life and stated that most of the time single tooth is involved [25]. The authors reported red discoloration in only 2 teeth out of their study material comprising of 79 teeth [25] (Figures 1 (a-c) • Systemic disorders (as alkaptonuria, erythropoietic porphyria, hyperbilirubinemia etc.) also can cause tooth discoloration or enamel hypoplasia. • In fluorosis, chalky white spots or brown marks are caused by excessive fluoride intake. . • Trauma may cause tooth discoloration . Trauma may change a tooth to a pink, yellow, or dark gray.

• Teeth discoloration • Blisters that take weeks to heal • brown or red urine Tests and diagnosis: Many signs of porphyria are similar to other more common diseases such as eczema, multiple sclerosis and irritable bowel syndrome. Moreover, because porphyria is rare, it can be difficult to diagnosis Some kids have discoloration of teeth because some pigment is mixed in as a tooth is forming (kinda like a fresco painting, where paint is mixed in wet plaster on a wall). The antibiotic tetracycline is a classic example of this, but it can also happen with too much fluoride or with conditions like porphyria or even sometimes newborn jaundice Discoloration of teeth. 1. Discoloration of teeth Exogenous and Endogenous Stains. 2. Staining Staining of teeth may result from pigments or colored substance takent into mouth such as: Tobacco Medicine Dentifrice Food (substance in diet) 3. Causes of discoloration of teeth. 4. Stains derived from substance in the mouth are designated Exogenous. Clinical Signs. The age at which clinical signs become apparent varies substantially — 4 months to 8 years of age have been observed. Clinical signs include yellow-brown urine, erythrodontia (tooth discoloration), and porphyrinuria A red-brown discoloration of the teeth is the result and the affected teeth show a red fluorescence under ultra-violet light. Read Also: Hypoplastic Enamel Treatment in Permanent Anterior Teeth of a Child Congenital hyperbilirubinaemia: The breakdown products of haemolysis will cause a yellow-green discoloration. Mild neonatal jaundice is.

The first feline model of human congenital erythropoietic porphyria (CEP) due to deficient uroporphyrinogen III synthase (URO-synthase) activity was identified by its characteristic clinical phenotype, and confirmed by biochemical and molecular genetic studies. The proband, an adult domestic shorthair cat, had dark-red urine and brownish discolored teeth with red fluorescence under ultraviolet. Erythrodontia: a reddish or reddish-brown discoloration of the teeth. Erythrocyte: a mature red blood cell. Erythropoietic: pertains to the production of red blood cells. Erythropoietic Porphyria (EPP): a cutaneous porphyria due to the deficient activity of the enzyme, ferrochelatase Loss of tooth vitality (when the pulp gets infected or damaged it can die and cause discoloration). Intake of drugs such as tetracycline. Chemicals such as excess fluoride. Certain disease states that occur during periods of tooth development such as: Hepatitis, Biliary disease, Erythroblastosis Fetalis and Porphyria Start studying Developmental Defects of Dentine AND Tooth Discoloration (T1-4)*. Learn vocabulary, terms, and more with flashcards, games, and other study tools

Congenital Erythropoietic Porphyria - Metabolic Disorders

Porphyriacan lead to deposits of porhyrins in the enamel

discoloration of teeth and management - SlideShar

  1. WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms Bruising or discoloration, Constipation, Cracks at corner of mouth and Damaged teeth enamel and including Bruise or contusion, Constipation (adult) and Irritable bowel syndrome
  2. Vitrocin Capsule is used to prevent & treat certain types of infections such as sexually transmitted infections, respiratory tract infections, bacterial infections, eye infections, an infection spread through the bite of infected ticks, lice, mites (rickettsial infections) and serious infections caused by bacterium Bacillus anthracis (anthrax including inhalational anthrax)
  3. erythrodontia: [ ĕ-rith″ro-don´she-ah ] reddish brown pigmentation of the teeth
  4. Tooth discoloration those with sodium perborate and water alone and frequently is the result of leaking or discolored therefore need not be used routinely.4,5,29 With a restorations. In such cases, cleaning the pulp cham- plastic instrument, pack the pulp chamber with the ber and replacing the defective restorations will paste
  5. o Porphyria cutanea tarda (PCT) This is the commonest porphyria in global terms, and is due to a defect in hepatic uroporphyrinogen decarboxylase. Uroporphyrin accumulates and causes skin lesions, Teeth show a brown discoloration (erythrodontia), and fluoresce red in UV light

Tooth discoloration - Wikipedi

Causes of Tooth Discoloration There are many ways teeth can become discolored, including: Antibiotic tetracycline use before age 8 Consuming foods or drinks that temporarily stain the teeth, like tea, coffee, red wine, or iron-containing liquids Smoking and chewing tobacco Genetic defects that affect the tooth enamel, like dentinogenesis and. Yellow teeth can be caused by external factors. In most situations, teeth become yellow as a result of interaction with specific items. When dental hygiene is not immaculate, the staining particles of these items adhere to the surface of the teeth, producing discoloration. The following items can discolor teeth and belong to many major families - Porphyrin deposition may lead to corneal ulcers and scarring, reddish-brown discoloration of the teeth (erythrodontia), and mild bone loss and/or expansion of the bone marrow. Diagnosis - Visibly dark discoloration of urine and characterized by the increase of uroporphyrinogen I and coproporphyrinogen isomers

About Porphyria - American Porphyria Foundatio

Hepatoerythropoietic porphyria (HEP) is an extremely rare genetic disorder characterized by deficiency of the enzyme, uroporphyrinogen decarboxylase. (photosensitivity). Affected areas of skin can scar and become discolored. There may be risk of bacterial infection. urine, teeth, and bones. The major symptom of this disorder is. Permanent scarring of the skin. Overgrowth or loss of hair. Urine discoloration (red or orange) Basically, the condition is an oversensitivity to the sun! The symptoms of acute porphyria, or the type that affects the nervous system are: Abdominal pains. Pain in the limbs, back, chest. Seizures Porphyria refers to a group of related disorders caused by a disruption in one of the steps involved in creating a protein called heme. Heme is an integral part of hemoglobin, the molecule that carries oxygen inside red blood cells. There are eight main types of porphyria. The two main categories are acute or cutaneous (skin) depending on the. Hepatoerythropoietic porphyria (HEP) affects the skin and is due to a build-up of damaging chemicals in the body.Symptoms usually begin in infancy and include extreme sun sensitivity, extra body hair, discolored teeth, and anemia.Over time, people with HEP may lose skin, bone or develop scarring in sun-exposed areas Dental Stains and Tooth Discoloration. Tooth discolouration is defined as any change in the hue, colour, or translucency of a tooth due to any cause; restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or haemorrhage may be responsible.. Tooth discoloration can be classified as either extrinsic or intrinsic

Gunther Disease - an overview ScienceDirect Topic

discoloration has become rare and one such case of discoloration of teeth due to administration of tetracyclines is reported here and discussed in detail. Key words: Staining of teeth, Tetracyclines, Intrinsic and extrinsic staining, Drug induced discoloration Department of Oral Medicine& Radiology Kamineni Institue of Dental Sciences, Narketpally Intrinsic tooth discoloration can be a significant cosmetic, and in some instances, functional, problem. Loss of vitality secondary to trauma or infection frequently results in tooth discoloration which is not responsive to conventional endodontic therapy. Similarly fluorosis, tetracycline staining, localised and chronological hypoplasia, an Congenital erythropoietic porphyria (CEP or Gunther disease) is an extremely rare subtype of the non-acute group, estimating a prevalence of <0.9 in 1 000 000 [1, 2]. All organs are vulnerable to the porphyrin accumulation effects, but the most affected ones are the skin, hematopoietic system, teeth, bones and sclera Congenital erythropoietic porphyria (Gunther disease) is a rare congenital form of porphyria, and may be associated with red or brown discolored teeth. Hyperbilirubinemia during the years of tooth formation may make bilirubin incorporate into the dental hard tissues, causing yellow-green or blue-green discoloration

What are the symptoms of Tooth Discoloration ? Intrinsic causes are usually seen at the time of teeth eruption. In hereditary conditions like erythroblastosisfetalis and porphyria the teeth are. The brown discoloration of the bones and teeth in association with bright orange fluorescence of the bones, teeth, and urine with UV light was considered to be pathognomonic for porphyria. Open in a separate windo Discolored deciduous teeth in a six-year-old child with a history of erythroblastosis fetalis. (From Ishikawa's Color Atlas of Oral Pathology. Ishikawa G, Waldron C. St, Louis: Ishiyaku Euro-America, 1987.) Fig. 3-6. Treatment: Usually none is necessary. Porphyria. This is a disorder of porphyrin metabolism which results in increased formation. Porphyria (red) Superficial tooth discoloration is usually caused by poor oral hygiene or habits such as smoking, consuming certain foods and beverages (such as tea), or taking drugs such as iron, chlorhexidine, or long term oral antimicrobials. In some cultures chewing betel causes staining

Congenital erythropoietic porphyria (CEP) is an autosomal recessive cutaneous porphyria caused by mutations in the gene coding for uroporphyrinogen III synthase (UROS).1,2 Phototoxic reactions result from the accumulation of biologically inert type I porphyrins, predominantly in the skin, red blood cells, bones, and teeth Keywords: Tooth discoloration, esthetic problems, tooth staining, treatment outcomes, extrinsic stains. Introduction It is widely recognized that today's youth and appearance oriented culture prizes an attractive smile and white teeth, with sales of whitening products rising dramatically in the past decade. Some of these product hypertrichosis; blood and teeth, skin biopsy dyspigmentation face and suggestive of porphyria arms, teeth discoloration. 2 21/M Dark skin, dark urine, Hb = 12.3 mg/dl, Normocytic photosensitivity, normochromic anemia, urine sclerodermoid skin of face, porphyrins ↑↑, blood blisters and scars on hand, porphyrins↑↑, liver enzymes ↑ ropoietic porphyria (CEP) results from a defect in por-phyrin metabolism that is characterized by excessive excretion of porphyrins in the urine and feces. Deposi-tion primarily of uroporphyrin I in tissues, especially the bones and teeth, causes brownish-red discoloration, and exposure of the teeth or bones to long-wavelengt

Even medications that are used in psychiatric illnesses today may place susceptible patients at risk for porphyria. Oral treatment: The red/brown discoloration in teeth may be more pronounced in deciduous teeth since the disorder affects both the enamel and dentin in formation. The dentin only is affected in permanent teeth (Neville et al. 1995) CCongenital erythropoietic porphyria and its rarity in ongenital erythropoietic porphyria and its rarity in IIndian siblingsndian siblings Sukhmani Kaur Brar1, Figure 3: (a-b) Pink fl uorescence of the teeth. A brownish discoloration of the urine (c) visible to the naked eye and (d) showing pink fl uorescenc This deficiency leads to hemolytic anemia, photosensitivity, blistering of the skin, and deposition of red-brown pigments in the bones and teeth. The literature regarding the dental aspects of this disorder is briefly reviewed and the preventive, restorative, and esthetic dental management of a 4-year-old child with congenital erythropoietic. Porphyria occurs in three forms. Congenital porphyria appears early in childhood as a fault of the pigment metabolism, possibly inherited as a mendelian recessive. Porphyria cutanea tarda is a relatively rare inherited fault of pyrrole metabolism characterized by the excretion of various types of porphyrin, mostly uroporphyrin. Acute porphyria manifests itself by gastrointestinal symptoms and. Porphyria cutanea tarda (PCT), the only chronic hepatic porphyria, has a prolonged course of liver damage and photosensitivity. Erythropoietic porphyrias present in childhood with photosensitivity. Features of CEP include extreme photosensitivity, hemolytic anemia, erythrodontia (red discoloration of teeth), hypertrichosis, ocular.

Porphyria; red discoloration of teethHow To Restore Severely Discolored Teeth - Spear Education

Extrinsic color depends on material absorption on the enamel surface. Any change in enamel, dentin, or coronal pulp structure can cause a change of the light-transmitting properties of the tooth - teeth discolouration. Tooth Discolouration. Tooth discoloration varies in etiology, appearance, location, severity, and affinity to tooth structure Congenital erythropoietic porphyria Hepatoerythropoietic porphyria: Eroded tooth enamel: Bulimia: Loss of deciduous and permanent teeth by late childhood: Papillon-Lefèvre syndrome Haim-Munk syndrome: Premature dentition (Natal teeth) Pachyonychia congenita type II: Grey-green discoloration of the mid-portion of permanent teeth


Tooth Discoloration COLOUR. Teeth made of many colours, with natural gradation from the darker cervical to the lighter incisal third e.g. Congenital erythropoietic porphyria (Inherited causes) e.g. Amelogenesis Imperfecta e.g. Dentinogenesis Imperfecta (Iatrogenic causes) Tetracycline Minocycline Fluorosis (Traumatic causes) Enamel. Porphyria is an incurable genetic disease, the symptoms of which align perfectly with those ascribed to vampires. Sufferers shun bright light because it irritates their skin and hurts their eyes. Flourosis: This is caused by excessive fluoride intake that later on gives a chalky white or brown-black appearance to the teeth. Congenital erythropoietic porphyria: This is an enzyme deficiency in the red blood cells that results to excessive photosensitivity and red-brown discolored teeth in children The discoloration my appear as spots, streaks or bands on the nail surface. Yellow to brown discoloration of teeth and fingernails is a common occurrence in long-term smokers. hemosiderosis, hyperbilirubinemia, kidney failure, liver disease, Peutz-Jeghers syndrome, porphyria, systemic lupus erythematosis (SLE), and acquired. Dental discoloration - causes and treatment of yellowness and stains on teeth. Share. Pin. Tweet. Send. Share. Send. The photo is illustrative. From the archive MV. In all the colors of the rainbow. Teeth have many shades. The individual natural color of the teeth is determined by dentin, but the color, transparency, thickness and degree of. Your results will be determined by how dark your teeth are and the cause of the discoloration. Last medically reviewed on September 30, 2019 Medically reviewed by Christine Frank, DDS — Written.